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Leadscope has written numerous articles and presented at international conference. Please contact us if you would like re-prints of any of these articles.

Huang, Y.; Blower, P. E.; Yang, C.; Barbacioru, C.; Dai, Z.; Zhang, Y.; Xiao, J. J.; Chan, K. K.; and Sade, W. Correlating gene expression with chemical scaffolds of cytotoxic agents: ellipticines as substrates and inhibitors of MDR1 (ABCB1), Pharmacogen. J. 2004, in press.

Yang, C.; Cross, K.; Myatt, G.; Blower, P.; Rathman, J. Building Predictive Models For PTP1B Inhibitors Based On Discriminating Structural Features By Reassembling Medicinal Chemistry Building Blocks, J. Med. Chem., 2004, 47, 5984-5994.

Myatt, G.J.; Zhengming, C.; Yang, C.; Cross, K.; Blower, P. Data Mining and Visualization in Drug Discovery, AAPS Newsletter, September 2004 16-19.

Blower, P.; Cross, K.; Fligner, M.; Myatt, G.; Verducci, J.; and Yang, C. Systematic analysis of large screening sets, Curr. Drug Disc. Technol., 2004, 37-47.

Cross, K.P.; Myatt, G.; Yang, C.; Fligner, M.F.;Verducci, J.S.; Blower, Jr., P.E. Finding Discriminating Structural Features by Reassembling Common Building Blocks, J. Med. Chem., 2003, 46, 4770-4775.

Blower, P. E. Jr.; Yang, C; Fligner, M. A.; Verducci, J. S.; Yu, L.; Richman, S.; Weinstein, J. N. Pharmacogenomic Analysis: Correlating Molecular Substructure Classes with Microarray Gene Expression Data, Pharmacogen. J. 2002, 2, 259-271.

Fligner, M. A.; Verducci, J. S.; Blower, P. E. Jr. A Modification of the Jaccard/Tanimoto Similarity Index for Diverse Selection of Chemical Compounds Using Binary Strings, Technometrics, 2002, 44, 110-19.

P. Blower, M. Fligner, J. Verducci, and J. Bjoraker; On Combining Recursive Partitioning and Simulated Annealing To Detect Groups of Biologically Active Compounds, J. Chem. Inf. Comput. Sci., 2002, 42, 393-404.

Yang, C.; Bakshi, B.R.; Rathman, J.F.; and Blower Jr., P. E. Multiscale and Bayesian approaches to data analysis in genomics highthroughput screening, Curr. Opin. Drug Disc. Devel. 2002, 5

Johnson, D. E.; Blower, P. E., Jr.; Myatt, G. J.; Wolfgang, G. H. I. Chem-tox informatics: data mining using a medicinal chemistry building block approach, Curr. Opin. Drug Discovery Dev. 2001, 4, 92-101.

Roberts, G.; Myatt, G. J.; Johnson, W. P.; Cross, K. P.; Blower, P. E. Jr. LeadScope: Software for Exploring Large Sets of Screening Data, J. Chem. Inf. Comput. Sci. 2000, 40, 1302-1314.

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