Drugs Repro-Developmental Database**

Drugs Repro-Developmental Database**

Locate Reproductive-Developmental toxicity findings for drug-like chemicals

Description

Comprehensive high quality database containing reproductive and developmental studies

Features

  • Includes 58 drugs and drug products filed in New Drug application (NDA) reviews.
  • Test system includes mostly rats and studies include mostly Segment II (Developmental) studies.
  • The compounds are stratified across carcinogenic and genotoxic potentials.
  • Studies include:
    • Maternal toxicity
    • Offspring toxicity
      • survival
      • growth
      • morphology
  • Access to the raw data in SD and XML file formats, using the public ToxML controlled vocabulary.

Requirements

Leadscope Enterprise, Leadscope Hosted or Leadscope Personal

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