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FDA CFSAN 2008 Genetox Database*
High quality genetic toxicity database from the US FDA CFSAN
(Center for Food Safety and Applied Nutrition).
Includes 572 chemical structures and 4045 genetic toxicity tests on the following endpoints: bacterial mutagenesis, in vitro mammalian mutagenesis, in vitro mammalian chromosomal aberrations and in vivo mammalian micronuclei.
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FDA CDER 2008 Genetox Database*
High quality genetic toxicity database from the US FDA CDER
(Center for Drug Evaluation and Research).
Genetic toxicity information extracted from pharmacological reviews contained in New Drug Approvals (NDA). Endpoints include: bacterial mutagenesis, in vitro mammalian mutagenesis, in vitro mammalian chromosomal aberrations and in vivo mammalian micronuclei.
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FDA CFSAN 2008 Acute Toxicity Database*
High quality acute toxicity database from the US FDA CFSAN
(Center for Food Safety and Applied Nutrition).
Comprehensive high quality Acute toxicity data from the US FDA CFSAN (Center for Food Safety and Applied Nutrition) PAFA (Priority-based Assessment of Food Additives) database
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FDA Marketed Drugs Database*
High quality marketed drug database from the US FDA.
Historical marketed drug records from FDA and other Government sites including structures for drug products and parents of the active ingredients along with the therapeutic indications
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FDA CDER 2008 Repro-Developmental*New
Comprehensive high quality database containing reproductive
and developmental studies from the US FDA CDER (Center for Drug Evaluation and Research).
Repro-developmental toxicity information extracted from FDA CDER with the following results: Maternal toxicity, fertility, functional toxicity, reproductive toxicity, Offspring toxicity, survival, growth toxicity, functional toxicity, morphology, and LOEL or NOEL specified with critical effects.
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FDA CFSAN 2008 Repro-Developmental*
Comprehensive high quality database containing reproductive
and developmental studies from the US FDA CFSAN (Center for Food Safety and Applied Nutrition).
Repro-developmental toxicity information extracted from FDA PAFA (Priority-based Assessment of Food Additives) and FCNs (Food Contact Notifications) with the following results: Maternal toxicity, fertility, functional toxicity, reproductive toxicity, Offspring toxicity, survival, growth toxicity, functional toxicity, morphology, and LOEL or NOEL specified with critical effects.
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FDA CDER 2008 Chronic/subchronic Database*
High quality chronic toxicity database from the US FDA CDER
(Center for Drug Evaluation and Research).
Chronic toxicity data from CDER including information on clinical signs, clinical pathology, clinical chemistry, hematology and histopathology. Data captured on rat and mouse for 1 year, 6 month and 3 month studies.
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FDA CFSAN 2008 Chronic/subchronic Database*
High quality chronic/subchronic toxicity database from the US FDA CFSAN
(Center for Food Safety and Applied Nutrition).
Comprehensive high quality chronic/subchronic toxicity database from the US FDA CFSAN (Center for Food Safety and Applied Nutrition).
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FDA SAR Genetox Database
High quality genetic toxicity database to be used as a resource for training sets.
Includes 9,472 compounds with 145,071 test results from FDA NDA (new drug approval), FCN (food contact notification), NTP, CCRIS, and other primary data sources. All structures confirmed for accuracy and all conflicing test calls resolved with FDA consultation.
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* Leadscope Database Manager is recommended for multiple databases
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FDA SAR Carcinogenicity DatabaseNew
High quality carcinogenicity database to be used as a resource for training sets.
Includes 3,113 compounds with 9,557 test results from FDA CDER (Center for Drug Evaluation and Research), CFSAN (Center for Food Safety and Applied Nutrition), NTP, CCRIS, CPDB and other primary data sources. All structures confirmed for accuracy and all conflicing test calls resolved with FDA consultation.
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* Leadscope Database Manager is recommended for multiple databases
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Leadscope Database Manager
Recommended to search and combine databases
Combine, manage, search and visualize multiple FDA databases and import your own sets of chemical structures and associated data. Enables access to ToxML associated with chemical structures.
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