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Non-human Genetic Toxicity Suite*
Non-human Genetic Toxicity Suite*
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The Leadscope Model Applier
Compare predicted values with actual values
Description
Models
Software
Requirements
Models to support decision making processes on genotoxic potential of organic chemicals.
Model endpoints - gene mutation
in vitro microbial composite
in vitro microbial Salmonella (composite)
in vitro microbial E. coli composite
in vitro microbial E. coli w strains
in vitro fungi yeast composite
in vitro fungi yeast S. cerivisea
in vivo Drosophila composite
in vivo Drosophila sex linked recessive lethal
in vivo Drosophila heritable translocations
in vivo mammalian composite
in vivo mammalian dominant lethal
in vitro CHO V79 hgprt
Model endpoints - DNA damage
in vitro UDS composite
in vitro UDS rat hepatocytes
in vitro UDS human lymphocytes
Model endpoints - clastogenicity
in vivo micronucleus composite
in vivo micronucleus mouse
in vivo chromosome aberrations composite
in vivo chromosome aberrations mouse
in vivo chromosome aberrations other rodent
Stand-alone product with read-only models
Test structures entered in SMILES or MOL/SDF formats
Batch predictions
Windows XP or Vista with at least a Pentium 4, 1.0GHz processor (or equivalent) with Minimum 1.0 GB of RAM and 1 GB of disk space
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