Non-human Genetic Toxicity Suite*

Non-human Genetic Toxicity Suite*
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  • Models to support decision making processes on genotoxic potential of organic chemicals.
  • Model endpoints - gene mutation
    • in vitro microbial composite
    • in vitro microbial Salmonella (composite)
    • in vitro microbial E. coli composite
    • in vitro microbial E. coli w strains
    • in vitro fungi yeast composite
    • in vitro fungi yeast S. cerivisea
    • in vivo Drosophila composite
    • in vivo Drosophila sex linked recessive lethal
    • in vivo Drosophila heritable translocations
    • in vivo mammalian composite
    • in vivo mammalian dominant lethal
    • in vitro CHO V79 hgprt
  • Model endpoints - DNA damage
    • in vitro UDS composite
    • in vitro UDS rat hepatocytes
    • in vitro UDS human lymphocytes
  • Model endpoints - clastogenicity
    • in vivo micronucleus composite
    • in vivo micronucleus mouse
    • in vivo chromosome aberrations composite
    • in vivo chromosome aberrations mouse
    • in vivo chromosome aberrations other rodent
  • Stand-alone product with read-only models
  • Test structures entered in SMILES or MOL/SDF formats
  • Batch predictions
  • Windows XP or Vista with at least a Pentium 4, 1.0GHz processor (or equivalent) with Minimum 1.0 GB of RAM and 1 GB of disk space

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