The models in the Human Adverse Urinary Tract Suite intend to support regulatory decision making processes.

Description

The endpoints covered by this suite of models include:

• Bladder Disorders
• Blood in Urine Disorders
• Kidney Disorders
• Kidney Function tests
• Nephropathy Disorders
• Urolithiasis Disorders

Applicability domain defined by nearest neighbor analysis - explicit comparison of structural feature representations and coverage of test sets vs. the model

Leadscope Model Applier Software Features

• Stand-alone product with read-only models
• Test structures entered in SMILES or MOL/SDF formats
• Able to predict compounds in batches

Requirements

• Windows XP, Vista, 7, or 8 with a minimum 1.0GHz processor, a minimum of 1.0 GB of available memory, and a minimum of 10 GB of available disk space