SAR Genetox Database
$2,500
One-year license
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One-year license
Request Licensing Information
A resource for developing genetic toxicity training sets
Use the Leadscope Use Leadscope to identify active classes of compound
Explore in-depth genetic toxicity data for compounds of interest
- High quality genetic toxicity database with validated structures to be used as a resource for preparing training sets
- Includes 8,412 compounds with 145,071 test results from FDA NDA (new drug approval), FCN (food contact notification), NTP, CCRIS, and other primary data sources
- Structures confirmed for accuracy
- Provides structures in SAR, neutral and tested forms
- Includes explicit test protocols to judge the reliability of studies and calls
- Includes the following genetic toxicity calls:
Study Type Number of SAR Structures Total Number of Structures Number of Tests Bacterial mutagenesis 4,890 5,791 131,963 Mammalian mutagenesis 1,161 1,329 4,985 In vitro chromosome aberration 1,033 1,211 4,951 In vivo chromosome aberration 232 285 615 In vivo micronucleus 618 717 2,232 In vitro micronucleus 111 127 325 Total 7,015 8,412 145,071
- Call conflicts resolved with FDA consultation
- Leadscope® Enterprise, Leadscope® Hosted and Leadscope® Personal
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