High quality carcinogenicity database with validated structures to be used as a resource for preparing training sets
Includes 1,634 compounds with 9,557 test results from FDA CDER (Center for Drug Evaluation and Research), CFSAN (Center for Food Safety and Applied Nutrition), NTP, CCRIS, CPDB and other primary data sources
Structures confirmed for accuracy
Provides structures in SAR, neutral and tested forms
Includes explicit test protocols to judge the reliability of studies and calls
Provides carcinogenicity study calls for:
Endpoint
Number of SAR Structures
Number of Tests
Male Rat
1150
2,321
Female Rat
1137
2,057
Male Mouse
1086
1,852
Female Mouse
1108
1,831
Total
1,634
9,557
Call conflicts resolved with FDA consultation
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