2010 Drugs Genetox Database**

2010 Drugs Genetox Database**
$250
One-year license

Rapidly access genetic toxicity data for drug-like chemicals

Easily identify similar chemical substances


Use the Leadscope Database Viewer to identify compounds based on chemical feature


Explore in-depth chronic and sub-chronic data for compounds of interest
  • High quality genetic toxicity database including drug-like chemical substances
**Created under a CRADA with the US FDA CDER (Center for Drug Evaluation and Research)
  • Includes 289 drugs and drug products with detailed genetic toxicity test data (5,690 tests).
  • Genetic toxicity information extracted from pharmacological reviews contained in New Drug Application (NDA) reviews and other memos on the following endpoints:
    • bacterial mutagenesis tests
    • In vitro mammalian mutagenesis tests
    • In vitro chromosome aberration tests
    • In vivo chromosome aberration tests
    • n vivo micronucleus tests
  • The compounds overlap with the CDER Chronic/ Subchronic database
  • Access to the raw data in SD and XML file formats, using the public ToxML controlled vocabulary
  • A database viewer is provided with the data and requires Windows 2000 or XP with at least a PIII 700MHz processor (or equivalent) with 256MB of RAM and 500MB of disk space.

Shopping Cart
0 items