Rodent Carcinogenicity Suite*

Rodent Carcinogenicity Suite*

Models to support decision making processes on carcinogenic potential of organic chemicals


This suite includes the following predictive models.
  • in vivo Endpoints:
    • Rodent
    • mouse
    • rat
    • female mouse
    • male mouse
    • female rat
    • male rat
  • in vitro Endpoints:
    • BALBc-3T3
    • C3H10T1-2
    • cell transformation
    • SHE
  • Applicability domain defined by nearest neighbor analysis - explicit comparison of structural feature representations and coverage of test sets vs. the model

    Leadscope Model Applier Application Features

    • Stand-alone product with read-only models
    • Test structures entered in SMILES or MOL/SDF formats
    • Batch predictions


    • Windows XP, Vista, 7, or 8 with a minimum 1.0GHz processor, a minimum of 1.0 GB of available memory, and a minimum of 10 GB of available disk space