Food Safety Acute Toxicity Database***

Food Safety Acute Toxicity Database***

Rapidly access chemical and acute toxicity for food ingredients


The Food Safety Acute Toxicity Database is a comprehensive, high quality source of acute toxicity for food additives.


  • Includes 1,069 direct food additives and 1,700 tests
  • Test system includes
    • rats: 949 chemicals
    • mice: 366 chemicals
    • Others include rabbits, guinea pigs, dogs, and monkeys: 221 chemicals
    • Route of exposure: mostly oral
  • Compound-level LD50 values recorded in FDA CFSAN PAFA database
  • Access to the raw data in SD and XML file formats, using the public ToxML controlled vocabulary


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