The Non-human Genetic Toxicity Model Suite includes predictive (Q)SAR models to evaluate the potential genotoxicity of test chemicals.
- Salmonella Mutagenicity
- E. coli Mutagenicity
- Mouse Lymphoma
- In Vitro Chromosome Aberrations
- In Vivo Micronucleus
Applicability domain defined by nearest neighbor analysis - explicit comparison of structural feature representations and coverage of test sets vs. the model FDA/CDER/Division of Drug Safety Research publications document the weight of evidence methods and data sources employed.
Leadscope Model Applier Application Features
- Stand-alone product with read-only models
- Test structures entered in SMILES or MOL/SDF formats
- Batch predictions
- Windows XP, Vista, 7, or 8 with a minimum 1.0GHz processor, a minimum of 1.0 GB of available memory, and a minimum of 10 GB of available disk space