Human Adverse Urinary Tract Effects Suite*

Human Adverse Urinary Tract Effects Suite*

The models in the Human Adverse Urinary Tract Suite intend to support regulatory decision making processes.


The endpoints covered by this suite of models include:
  • Bladder Disorders
  • Blood in Urine Disorders
  • Kidney Disorders
  • Kidney Function tests
  • Nephropathy Disorders
  • Urolithiasis Disorders
Applicability domain defined by nearest neighbor analysis - explicit comparison of structural feature representations and coverage of test sets vs. the model

Leadscope Model Applier Software Features

  • Stand-alone product with read-only models
  • Test structures entered in SMILES or MOL/SDF formats
  • Able to predict compounds in batches


  • Windows XP, Vista, 7, or 8 with a minimum 1.0GHz processor, a minimum of 1.0 GB of available memory, and a minimum of 10 GB of available disk space